When two reports surfaced last month of college
students contracting an infectious disease known as meningitis, many parents were greatly
alarmed by the dramatic and frightening news coverage. Judging by the numerous phone calls
received in pediatric offices and at the health department, there is considerable
confusion in parent’s minds about this illness. When parents read about a case of
meningitis or are told that their child’s classmate has this infection, how much do
they really have to worry? Of the different infectious diseases of childhood, meningitis
is probably the most respected by physicians and feared by parents. What exactly is this
dreaded disease?
We have three layers of tough protective linings
surrounding our brain and spinal cord. The term "meningitis" simply means
inflammation of the meninges. These infections arises from a number of sources, the most
common cause being viruses. Even though it occurs less frequently, bacterial meningitis
often results in more serious illness since bacterial cause more inflammation and
scarring.
The less worrisome viral form of meningitis
usually arises from an ordinary viral infection. The symptoms of viral (sometimes called
"aseptic") meningitis are generally mild and similar to those of other viral
ailments such as influenza or the common cold. Viral meningitis is rarely fatal and
recovery is usually complete.
Bacterial meningitis remains one of the most
important infectious diseases encountered by physicians who care for children.The
responsible organisms can severely damage or kill nerve and brain tissue, sometimes
inflicting permanent neurological injury if left untreated. The names of the bacteria that
cause the most cases of bacterial meningitis in children are the pneumococcus, Hemophilus
influenzae type b (nothing to do with the organism that causes the flu!), and
meningococcus, the latter being the organisms respnsible for last month’s widely
publized cases. Since the meninges are well insulated from the outside world, most cases
of bacterial meningitis arise from germs which enter the blood stream from the respiratory
tract and then spread to the meninges. These bacteria are transmitted from person to
person in nasal droplets and by sharing food and eating utensils. The incubation period is
usually two to 10 days after exposure and over 75% of those who will develop the illness
do so within a few days after they come in contact with an infected person. Therefore, by
the time parents read about a case of meningitis in the paper or learn that one of their
child’s classmates has been hospitalized with this infection, the danger to their
child has probably passed.
The symptoms of meningitis occur slowly or hit
suddenly, depending on the cause and the individual child’s age and susceptibility.
Since the early signs of meningitis -- fever, irritability and headache -- may be similar
to those of the flu or common cold, the diagnosis may be delayed while meningitis is still
in an early stage. This is why parents need to become familiar with its symptoms in order
to judge when prompt medical attention is needed.
As a general rule, the younger the child, the less
specific the symptoms. In infants, meningitis usually begins slowly. Irritability,
restlessness, an unusual high pitched cry, displeasure at being handled and poor feeding
may be the only symptoms. In toddlers and young children, additional symptoms correspond
to signs of meningeal inflammation- vomiting, drowsiness, sensitivity of the eyes to
light, severe headache and stiff neck. By far the most distinctive feature of meningitis
is the stiff neck, although in children below the age of one this symptom may not be
present until very late in the illness. In older children with meningitis, any neck
movement is so painful that the child tends to lie still with their neck straight. Since
children frequently complain of a stiff neck during the course of an upper respiratory
disease, a good test is for parents to ask their child to "kiss a knee." If the
child can bend their neck forward and flex their knee so that the knee can be
"kissed," the neck pain is probably not due to meningitis. This can be done
either with the child sitting or laying down position. Temperature may be high or even
normal, and in about 30 percent of cases convulsions occur. Bacterial meningitis is
characteristic in that symptoms progress rapidly and there is usually no period when the
child seems to "get better."
When a physician suspects meningitis, blood
samples are drawn and a lumbar puncture or "spinal tap" is done to obtain
cerebrospinal fluid (the liquid that bathes the brain and spinal cord). A needle is
inserted into the child’s lower back so a small amount of fluid can be withdrawn for
analysis. Although the very thought of a "tap," may alarm parents, the procedure
is safe and causes only minimal, if any discomfort to the child. Normally clear, the
cerebrospinal fluid becomes cloudy when bacterial meningitis is present because of an
accumulation of disease fighting white blood cells and disease causing bacteria. A medical
laboratory will often contribute to the diagnosis by identifying the causitiv organism
from the fluid obtained.
When bacterial meningitis is the presumed
diagnosis, a child must be admitted to the hospital for the administration of intravenous
antibiotics and fluids, as well as observation for complications. Should the tests of the
spinal fluid eventually prove negative, then the antibiotics are discontinued. However, if
bacterial meningitis is indeed confirmed, then the antibiotics will have been the most
important intervention in the youngster’s life.
Household and other close contacts of people with
certain kinds of bacterial meningitis may be given an antibiotic called Rifampin to
protect them against the development of meningitis. Taken as soon as possible (within 48
hours of contact) it can usually forestall illness. Rifampin may also be used during
outbreaks in daycare centers or nursery schools. Antibiotics are not effective against
viral forms of meningitis
A important step in the prevention of bacterial
meningitis was the development of the Hemophilius influenzae type B vaccine. Administered
at 2,4,6 and 15 months of age, the HIB vaccine has dramatically decreased the incidence of
hemophilius influenzae type B meningitis in children Since meningitis in older children
and adults is usually due to different bacteria, the Hib vaccine is not useful at later
ages. Vaccines available against meningococcal bacteria are of limited usefulness, their
effectiveness hampered by the need for an immunization that would protect against all the
different forms of this bacterium.
Despite medical advances, meningitis still lingers as a dangerous
disease for the pediatric population. Through knowledge of the disease and recognition of
its symptoms, parents can play a crucial role in its early recognition since immediate
treatment goes a long way towards preventing neurologic complications and saving lives.
Hopefully, the development of new vaccines in the future will do much to even further
reduce the incidence of this serious illness.