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Quick reference medical handouts used by Pediatric offices


Facts about Autism


What is autism?

  • Autism is a complex, life-long biological disorder of development that results in social interaction problems, communication difficulties, and restrictive or repetitive interests and behaviors. The prevalence of autism estimates run from approximately one-in-500 children, to one-in-1000 children, who might be affected by some form of the disorder.

  • Autism can be reliably diagnosed by or before age three. Parents and expert clinicians can usually detect symptoms during infancy, although a formal diagnosis is generally not made until the child fails to develop functional language by age two. Approximately 20 percent of children with autism reportedly experience a "regression"; that is, they have apparently normal development followed by a loss of communication and social skills.

  • Boys are three-to-four times more likely to be affected by autism than girls. Autism occurs in all racial, ethnic, and social groups.

  • Although there is currently no known cure for autism, autism is treatable. Persons with autism can make progress if they receive appropriate, individual intervention. Pre-school children who receive intensive, individualized, behavioral interventions show remarkable progress. In addition, limited pharmacological interventions are available to treat specific symptoms of autism.

What causes autism?

  • In the majority of cases, no specific underlying cause can be identified. However, a variety of factors are being investigated. These include infectious, metabolic, genetic, and environmental factors.

  • A working group convened by the NIH in 1995 reached a consensus that autism probably results from a genetic susceptibility that involves multiple genes.

  • To date, genetic causes for one disorder commonly accompanied by autism and one autism-spectrum disorder have been identifiedCFragile X and Rett syndrome, respectivelyCand genetic "hotspots" for more classic autism have been indicated. Fragile X is the most common, genetically inherited form of mental retardation currently known and produces many of the same behaviors and symptoms as autism. Rett syndrome, which affects only girls, is a progressive brain disease that produces a loss of language/social skills that is similar to autism and is classified as an autism spectrum disorder (ASD)

  • NIH research on possible genetic, infectious, immunological, and environmental causes and mechanisms of autism is underway.

Is there a relationship between autism and vaccines?

  • To date there is no conclusive evidence that any vaccine increases the risk of developing autism or any other behavior disorder.

  • Several epidemiological studies show no causal association between the measles/mumps/rubella (MMR) vaccine (or other measles-containing vaccines) and autism. In January 1990, the Institute of Medicine concluded that there was no evidence to indicate a causal relationship between autism and the diphtheria/tetanus/pertussis (DTP) vaccine or the pertussis component of the DTP vaccine. In 2001, the IOM concluded that there is no causal relationship, at a population level, between the MMR vaccine and ASDs.

  • Currently, no study provides definitive evidence of an association between autism and vaccines. However, continued research is needed to examine the mechanisms of autism and any possible relationship to vaccines.

see also:>

Missed developmental milestones are a clue to autism
Autism remains a medical mystery


courtesy of National Center for Education in Maternal and Child Health

 

As a reminder, this information should not be relied on as medical advice and is not intended to replace the advice of your child’s pediatrician. Please read our full disclaimer.

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