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| Quick reference medical handouts used
by Pediatric offices |

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Facts about Autism
What is autism?
- Autism is a complex, life-long biological
disorder of development that results in social interaction problems,
communication difficulties, and restrictive or repetitive interests and
behaviors. The prevalence of autism estimates run from approximately
one-in-500 children, to one-in-1000 children, who might be affected by some
form of the disorder.
- Autism can be reliably diagnosed by or before
age three. Parents and expert clinicians can usually detect symptoms during
infancy, although a formal diagnosis is generally not made until the child
fails to develop functional language by age two. Approximately 20 percent of
children with autism reportedly experience a "regression"; that
is, they have apparently normal development followed by a loss of
communication and social skills.
- Boys are three-to-four times more likely to be
affected by autism than girls. Autism occurs in all racial, ethnic, and
social groups.
- Although there is currently no known cure for
autism, autism is treatable. Persons with autism can make progress if they
receive appropriate, individual intervention. Pre-school children who
receive intensive, individualized, behavioral interventions show remarkable
progress. In addition, limited pharmacological interventions are available
to treat specific symptoms of autism.
What causes autism?
- In the majority of cases, no specific
underlying cause can be identified. However, a variety of factors are being
investigated. These include infectious, metabolic, genetic, and
environmental factors.
- A working group convened by the NIH in 1995
reached a consensus that autism probably results from a genetic
susceptibility that involves multiple genes.
- To date, genetic causes for one disorder
commonly accompanied by autism and one autism-spectrum disorder have been
identifiedCFragile X and Rett syndrome, respectivelyCand genetic
"hotspots" for more classic autism have been indicated. Fragile X
is the most common, genetically inherited form of mental retardation
currently known and produces many of the same behaviors and symptoms as
autism. Rett syndrome, which affects only girls, is a progressive brain
disease that produces a loss of language/social skills that is similar to
autism and is classified as an autism spectrum disorder (ASD)
- NIH research on possible genetic, infectious,
immunological, and environmental causes and mechanisms of autism is
underway.
Is there a relationship between
autism and vaccines?
- To date there is no conclusive evidence that
any vaccine increases the risk of developing autism or any other behavior
disorder.
- Several epidemiological studies show no causal
association between the measles/mumps/rubella (MMR) vaccine (or other
measles-containing vaccines) and autism. In January 1990, the Institute of
Medicine concluded that there was no evidence to indicate a causal
relationship between autism and the diphtheria/tetanus/pertussis (DTP)
vaccine or the pertussis component of the DTP vaccine. In 2001, the IOM
concluded that there is no causal relationship, at a population level,
between the MMR vaccine and ASDs.
- Currently, no study provides definitive
evidence of an association between autism and vaccines. However, continued
research is needed to examine the mechanisms of autism and any possible
relationship to vaccines.
see also:> Missed developmental milestones are a clue to autism
Autism remains a medical mystery
courtesy of National Center for Education in Maternal and Child Health
As a reminder, this information should not be relied on as
medical advice and is not intended to replace the advice of your childs pediatrician.
Please read our full disclaimer.
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